Humbling words from Calvin (here quoted by Spurgeon). Despite our proud resistance of the fact, God does not need us; but in His grace, He allows us to play a small part in His grand and continuing storyline of redemption.
“It is of the utmost importance to us to be kept humble. Consciousness of self-importance is a hateful delusion, but one into which we fall as naturally as weeds grow on a dunghill. We cannot be used of the Lord but what we also dream of personal greatness, we think ourselves almost indispensable to the church, pillars of the cause, and foundations of the temple of God. We are nothings and nobodies, but that we do not think so is very evident, for as soon as we are put on the shelf we begin anxiously to enquire, “How will the work go on without me?” As well might the fly on the coach wheel enquire, “How will the mails be carried without me?” Far better men have been laid in the grave without having brought the Lord’s work to a standstill, and shall we fume and fret because for a little season we must lie upon the bed of languishing? If we were only put on one side when apparently we could be easily spared, there would be no rebuke to our pride, but to weaken our strength in the way at the precise juncture when our presence seems most needed, is the surest way to teach us that we are not necessary to God’s work, and that when we are most useful he can easily do without us. If this be the practical lesson, the rough schooling may be easily endured, for assuredly it is beyond all things desirable that self should be kept low and the Lord alone magnified. 
 Charles Spurgeon, “Laid Aside: Why?” The Sword and Trowel, May 1876.